Leukemoid Reaction and Diagnosis (D/D from Chronic Myelocytic leukemia)
A leukemoid reaction is an increase in the white blood cell count, which can mimic leukemia. The reaction is actually due to an infection or another disease and is not a sign of cancer. Blood counts often return to normal when the underlying condition is treated. Sample Blood in EDTA is needed along with fresh blood smear. Definition If there is a persistent increase in the neutrophils, reactive and excessive leucocytosis with a count of 30,000 to 50,000 / µL, with the presence of immature and mature white cells in the peripheral the blood smear is called a Leukemoid reaction. Sometimes the lymphocytic reaction is maybe seen. This is not a primary marrow disorder, and this is due to the secondary to infections. The count varies from 50,000 to 100,000/cmm. with immature cells. Blast cells in the peripheral blood smears are not seen which is helpful to differentiate from leukemia. Extremely eleva...