Pathology fun

Introduction:-  Western blot is often used in research to separate and identify proteins. In this technique, a mixture of proteins is separated based on molecular weight, and thus by type, through gel electrophoresis. These results are then transferred to a membrane producing a band for each protein. The membrane is then incubated with labels antibodies specific to the protein of interest. The unbound antibody is washed off leaving only the bound antibody to the protein of interest. The bound antibodies are then detected by developing the film. As the antibodies only bind to the protein of interest, only one band should be visible. The thickness of the band corresponds to the amount of protein present; thus doing a standard can indicate the amount of protein present. The paper will first describe the protocol for western blot, accompanied by pictures to help the reader and theory to rationalize the protocol. This will be followed by the theoretical explanation of the procedure, and...

  Introduction:-  Medical informatics  is the intersection of information science, computer science, and  health  care. This field deals with the resources, devices, and methods required to optimize the acquisition, storage, retrieval, and use of information in  health  and biomedicine. Medical informatics is found at the intersection of healthcare and technology. It is where skills in both medical and computer sciences come together in an effort to improve healthcare and patient outcomes. Professionals in this hybrid field draw on expertise from both disciplines to put technology to its best use in patient care, clinical, and research settings. Types of Work in Medical Informatics Medical Informatics Professionals are tasked with using information technology to its greatest advantage in the healthcare industry. This means they are responsible for such tasks as: Creating, maintaining or facilitating new ways for medical facilities and practices to...

  The diagnosis of acute myocardial infarction (AMI) involves multiple clinical tools including physical assessment, ECG, and the evaluation of cardiac biomarkers. Electrocardiography produces a physiological signal that is frequently used for diagnosing heart problems, but it is incapable of adequately diagnosing AMI. Myoglobin, B-type natriuretic peptide (BNP), creatine kinase isoenzyme MB (CK-MB), and cardiac troponin T (cTn-T) are cardiac biomarkers frequently used for evaluating cardiac risk factors. Biomarker History Biomarkers have been in use since the 1960s and have continually improved to become more reliable when used to diagnosis a cardiac event. Aspartate Transaminase (AST) The first biomarker identified was Aspartate Transaminase (AST), and it was used frequently in the 1960s but was not cardiac muscle specific. Lactate Dehydrogenase (LDH) and Creatine Kinase (CK) Lactate dehydrogenase (LDH) and creatine kinase (CK) were used in the 1970s, and even though neither...

Blood is a specialized body fluid. It has four main components: plasma, red blood cells, white blood cells, and platelets. Blood has many different functions, including: transporting oxygen and nutrients to the lungs and tissues forming blood clots to prevent excess blood loss carrying cells and antibodies that fight infection bringing waste products to the kidneys and liver, which filter and clean the blood regulating body temperature The blood that runs through the veins, arteries, and capillaries is known as whole blood, a mixture of about 55 percent plasma and 45 percent blood cells. About 7 to 8 percent of your total body weight is blood. An average-sized man has about 12 pints of blood in his body, and an average-sized woman has about nine pints. The Components of Blood and Their Importance Many people have undergone blood tests or donated blood, but hematology - the study of blood -encompasses much more than this. Doctors who specialize in hematology (hematologists) are leading ...

Introduction The future paradigm of pathology will be digital. Instead of conventional microscopy, a pathologist will perform diagnosis through interacting with images on computer screens and performing quantitative analysis. The fourth generation of virtual slide telepathology systems, so-called virtual microscopy and whole-slide imaging (WSI), has allowed for the storage and fast dissemination of image data in pathology and other biomedical areas. These novel digital imaging modalities encompass high-resolution scanning of tissue slides and derived technologies, including automatic digitization and the computational processing of whole microscopic slides. Moreover, automated image analysis with WSI can extract specific diagnostic features of diseases and quantify individual components of these features to support diagnoses and provide informative clinical measures of the disease. Therefore, the challenge is to apply information technology and image analysis methods to exploit the new...